That statement did not age well.
As long as you do not need to work, need to visit restaurants, gyms, cafes, attend a college, attend various kinds of events nationwide – and live as an isolated hermit, this is true:
It comes as the Centers for Disease Control urges “universal mask use” anywhere outside the home.
Source: Joe Biden: Covid vaccination in US will not be mandatory – BBC News
In the not very distant future, vaccinations will also likely be mandatory for air and rail travel within the U.S. This is now required in Canada, for example.